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M519101
- Development stage
- Unknown
- Lead developer
- Nitto
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
M519101 is a topical anesthetic patch formulation containing a combination of lidocaine and prilocaine (also known as propitocaine in Japan). Developed by Maruho Co., Ltd., it is designed to provide local anesthesia and reduce pain associated with dermatological procedures, specifically laser treatment of angiomas. The patch formulation allows for controlled delivery of the anesthetic agents to the skin surface, stabilizing the procedural tolerance for patients undergoing laser therapy. It is currently in Phase 3 clinical development in Japan.
- Other names
- lidocaine/propitocaine patchlidocaine/prilocaine patch
02
Targets
SCN5A (Sodium channel protein type 5 subunit alpha)SCN2A (Voltage-gated sodium channel protein type 2 subunit alpha)SCN9A (Sodium channel protein type 9 subunit alpha)SCN8A (NaV1.6)SCN1A (Voltage-gated sodium channel protein type 1 subunit alpha)SCN3A (Sodium channel protein type 3 subunit alpha)SCN11A (NaV1.9)SCN10A (Sodium channel protein type X alpha subunit)SCN4A (Voltage-gated sodium channel protein type 4 subunit alpha)
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