Drug intelligence / Profile preview

Ma Ren Run Chang Soft Capsules

Development stage
Unknown
Lead developer
Rongchang Biopharmaceutical
Administration
Oral
01

Overview

Ma Ren Run Chang Soft Capsules (麻仁润肠软胶囊) is a Traditional Chinese Medicine (TCM) patent drug widely used in China for the treatment of constipation, particularly 'heat-type' constipation characterized by gastrointestinal heat accumulation, abdominal distension, and dry stools. The formulation is a soft capsule containing a mixture of traditional herbs, including hemp seed (*Fructus Cannabis* / Huo Ma Ren), bitter apricot seed (*Semen Armeniacae Amarum* / Ku Xing Ren), rhubarb (*Radix et Rhizoma Rhei* / Da Huang), costus root (*Radix Aucklandiae* / Mu Xiang), tangerine peel (*Pericarpium Citri Reticulatae* / Chen Pi), and white peony root (*Radix Paeoniae Alba* / Bai Shao). It functions by moistening the intestines, promoting peristalsis, and softening stool to facilitate easy evacuation. Developed and manufactured by companies such as Rongchang Pharmaceutical (Zibo) Co., Ltd. and Beijing Tongrentang Technologies, it has also served as an active comparator in clinical trials evaluating novel TCM therapies for constipation.

Brand names
Tongrentang
Other names
Maren Runchang Soft CapsulesMa Ren Run Chang Soft CapsuleMaren Runchang Soft Capsule麻仁润肠软胶囊
02

Targets

COL1A1 (Collagen type I alpha 1 chain)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)PTEN (Phosphatase and tensin homolog deleted on chromosome ten)

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