macrogol + potassium chloride + sodium chloride + sodium bicarbonate

Macrogol + potassium chloride + sodium chloride + sodium bicarbonate is an osmotic laxative combination developed by AUG Pharma for the treatment of chronic constipation. The primary active component, macrogol (polyethylene glycol), is a high molecular weight polymer that remains in the gastrointestinal tract, where it binds water molecules through hydrogen bonding. This action increases the osmotic pressure and water content of the stool, leading to softened feces and increased bowel motility through the stimulation of peristalsis. The inclusion of electrolytes (sodium chloride, sodium bicarbonate, and potassium chloride) is intended to maintain isotonicity and prevent the depletion of essential salts or systemic fluid imbalances during the laxative process. This formulation is typically administered as an oral solution prepared from a powder.

Brand names

Macrogol HexalMacrogol HEXAL plus Elektrolyte

Other names

Macrogol with electrolytesPolyethylene glycol with electrolytesPEG with electrolytesMacrogol 3350 with electrolytesMacrogol3350 with electrolytesMacrogol-3350 with electrolytes