Drug intelligence / Profile preview

macrogol cetostearyl ethers

Development stage
Unknown
Lead developer
BASF
Modality
Nanoparticles → Drug Delivery Systems, Small Molecules
Administration
Topical
01

Overview

Macrogol cetostearyl ethers are non-ionic surfactants formed by the ethoxylation of mixed fatty alcohols (mainly cetostearyl alcohol) with varying numbers of ethylene oxide units (typically between 2 and 33). They are used primarily as emulsifying agents and solubilizers in pharmaceutical creams and ointments for topical application. These compounds help stabilize oil-in-water emulsions and improve the sensory properties of formulations. Macrogol cetostearyl ethers are widely used in dermatological preparations for dry or sensitive skin conditions such as eczema[2][5][6][7]. They act by reducing surface tension between ingredients to form stable mixtures but do not have direct pharmacological activity on biological targets.

Brand names
Kolliphor CS 20Eumulgin B25Cetomacrogol
Other names
cetearethcetomacrogol 1000cetomacrogol1000cetomacrogol-1000PEG 20 cetostearyl etherPEG20 cetostearyl etherPEG-20 cetostearyl etherpolyethylene glycol monocetyl etherBrij-58Brij58Brij 58

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