Drug intelligence / Profile preview

maculosin

Development stage
Unknown
Modality
Peptides, Small Molecules
01

Overview

Maculosin is a naturally occurring cyclic dipeptide composed of L-proline and L‑tyrosine. It belongs to the class of pyrazine derivatives and alpha amino acid derivatives. Maculosin has been identified as a secondary metabolite in certain microorganisms and plants. Its mechanism of action is not fully characterized; however, it has been reported to exhibit biological activities such as phytotoxicity and antimicrobial effects in experimental settings. There are no approved therapeutic indications or clinical uses for maculosin at this time[1][3][6].

Other names
(3s,8ar)-3-(4-hydroxybenzyl)hexahydropyrrolo[1,2-a]pyrazine-1,4-dioneCyclo(L-Pro-L-Tyr)Cyclo(-Pro-Tyr)Cyclo(pro-tyr)Cyclo(L-prolinyl-L-tyrosine)Pyrrolo[1,2-a]pyrazine-1,4-dione, hexahydro-3-[(4-hydroxyphenyl)methyl]-, (3S,8aR)-
02

Targets

TYR (Tyrosinase)IspG (4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase)

Beyond the preview

Go deeper on maculosin.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on maculosin.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call