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Madu Tualang Honey is a Malaysian multifloral jungle honey produced by the rock bee (*Apis dorsata*), which builds hives on the branches of tall Tualang trees (*Koompassia excelsa*) found primarily in the north-western region of Peninsular Malaysia. It is a complex natural product and biologic (whole honey) rather than a purified small molecule. Preclinical studies have demonstrated that it possesses antimicrobial, anti-inflammatory, antioxidant, antimutagenic, antitumor, and antidiabetic properties, including antiproliferative effects against various cancer cell lines such as leukemia. In a clinical trial context, it is being investigated by Universiti Sains Malaysia as a prophylactic intervention for febrile neutropenia in patients with hematological malignancies, where it is compared against standard oral ciprofloxacin prophylaxis. Its therapeutic effects are attributed to its complex multicomponent composition, including various phenolics and flavonoids, rather than a single defined active ingredient.
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