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Magic mouthwash is a compounded oral rinse made from a combination of medications designed to relieve pain and inflammation associated with oral mucositis and other painful sores in the mouth and throat. It is not a single standardized product but rather a customizable prescription mixture prepared by compounding pharmacies according to individual patient needs. Commonly included ingredients are an antihistamine (such as diphenhydramine), an anesthetic (such as viscous lidocaine), an antacid (such as Maalox or Mylanta), sometimes corticosteroids (like dexamethasone or hydrocortisone), antifungals (like nystatin), antibiotics, or other agents. The mechanism of action depends on the specific components but generally includes local anesthesia for pain relief, anti-inflammatory effects, reduction of swelling, antimicrobial activity against bacteria and fungi, and improved coating/adherence to the oral mucosa[1][2][3][6][7].
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