Drug intelligence / Profile preview

magic mouthwash

Development stage
Phase 2
Lead developer
CutisPharma, Inc.
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Oral, Topical
01

Overview

Magic mouthwash is a compounded oral rinse made from a combination of medications designed to relieve pain and inflammation associated with oral mucositis and other painful sores in the mouth and throat. It is not a single standardized product but rather a customizable prescription mixture prepared by compounding pharmacies according to individual patient needs. Commonly included ingredients are an antihistamine (such as diphenhydramine), an anesthetic (such as viscous lidocaine), an antacid (such as Maalox or Mylanta), sometimes corticosteroids (like dexamethasone or hydrocortisone), antifungals (like nystatin), antibiotics, or other agents. The mechanism of action depends on the specific components but generally includes local anesthesia for pain relief, anti-inflammatory effects, reduction of swelling, antimicrobial activity against bacteria and fungi, and improved coating/adherence to the oral mucosa[1][2][3][6][7].

Brand names
First Mouthwash BLM
Other names
magic mouthwashmiracle mouthwashDuke’s magic mouthwashMary’s magic mouthwash
02

Targets

ErgosterolNaV (Voltage-gated sodium channels)GR (Glucocorticoid receptor)HRH1 (Histamine H1 Receptor)

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