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MagicTouch SCB
- Development stage
- Unknown
- Lead developer
- Concept Medical
- Modality
- Device-based Delivery → Drug Delivery Systems, Small Molecules
- Administration
- Intra-arterial
01
Overview
MagicTouch SCB is a sirolimus drug-coated balloon (SCB) catheter designed for the treatment of coronary artery disease, specifically targeting in-stent restenosis (ISR), small vessel disease, bifurcation lesions, and de-novo coronary lesions. Developed by Concept Medical, it utilizes proprietary Nanolutè technology to encapsulate sub-micron sized sirolimus particles within a biocompatible phospholipid carrier. This allows for rapid and effective transfer of sirolimus into the vessel wall during balloon inflation—achieving homogeneous drug distribution with minimal downstream exposure. The released sirolimus inhibits neointimal proliferation by acting as an mTOR inhibitor, reducing smooth muscle cell proliferation and thus preventing restenosis. The device is CE marked and has extensive commercial use in Europe, Asia, and the Middle East; it is currently under clinical investigation in the United States with multiple ongoing pivotal trials[1][2][3][5][7][8][9][10].
- Brand names
- MagicTouch SCB
- Other names
- Magic Touch sirolimus-coated balloonMagic Touch SCBSirolimus Drug Coated Balloon catheter (MagicTouch)
02
Targets
mTOR (Mammalian target of rapamycin kinase)
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