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magnesium acetate + dextrose monohydrate + sodium chloride + potassium acetate
- Development stage
- Approved
- Lead developer
- ICU Medical
- Modality
- Small Molecules
- Administration
- Intravenous
01
Overview
Magnesium acetate + dextrose monohydrate + sodium chloride + potassium acetate is a **sterile intravenous multiple-electrolyte and carbohydrate solution** marketed as **Normosol-M and 5% Dextrose Injection** and manufactured by ICU Medical. It contains dextrose monohydrate together with sodium, potassium, magnesium, chloride, and acetate sources, and is used for **parenteral maintenance of routine daily fluid and electrolyte requirements with minimal carbohydrate calories**. Its pharmacologic effect is not mediated through a single receptor or enzyme target; rather, it acts by **replacing water, electrolytes, and a small caloric source**, helping maintain extracellular fluid composition, acid-base balance through acetate metabolism to bicarbonate, and magnesium repletion during prolonged parenteral therapy when needed.
- Brand names
- Normosol-M and 5% Dextrose Injection
- Other names
- Multiple Electrolytes and 5% Dextrose Injection Type 1magnesium acetate + dextrose monohydrate + sodium chloride + potassium acetate
02
Targets
KCNQ1 (Potassium voltage-gated channel subfamily KQT member 1)SLC2A4 (Solute carrier family 2 facilitated glucose transporter member 4)NaV (Voltage-gated sodium channels)
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