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magnesium ascorbyl phosphate + fluoride
- Development stage
- Phase 3
- Lead developer
- Lion Corporation
- Modality
- Small Molecules
- Administration
- Topical
01
Overview
Magnesium ascorbyl phosphate + fluoride is a combination therapeutic formulation used in oral care, specifically in dentifrices (toothpastes). Magnesium ascorbyl phosphate (MAP) is a stable, water-soluble derivative of Vitamin C that acts as an antioxidant and a precursor for collagen synthesis, which helps in maintaining the integrity of gingival tissues and reducing inflammation, redness, and bleeding associated with gingivitis. Fluoride, typically included as sodium fluoride or sodium monofluorophosphate, provides anti-caries protection by promoting the remineralization of dental enamel and inhibiting the metabolic processes of plaque-forming bacteria. This combination is primarily developed and marketed by companies like Lion Corporation for the treatment of gingivitis and the prevention of dental decay.
- Other names
- L-ascorbic acid 2-phosphate magnesium salt + fluorideMAP + fluoride
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