Drug intelligence / Profile preview

magnesium carbonate

Development stage
Phase 2
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral, Irrigation
01

Overview

Magnesium carbonate is an inorganic compound used primarily as a mineral supplement and antacid. It is indicated for the prevention and treatment of low magnesium levels in the blood (hypomagnesemia) and for symptomatic relief of heartburn, indigestion, upset stomach, or other conditions caused by excess stomach acid. As an antacid, it works by neutralizing gastric hydrochloric acid through a chemical reaction that produces carbon dioxide and magnesium chloride. Magnesium is essential for normal cellular function including nerve transmission, muscle contraction/relaxation (including cardiac muscle), bone health, and enzymatic reactions[2][3][4]. Magnesium carbonate is available over-the-counter in various formulations. As an antacid, it works by neutralizing gastric hydrochloric acid. It also acts as a glutamate (NMDA) receptor blocker.

Brand names
MagonateMag-CarbDewees CarminativeAcid GoneGavisconMagnebind 400 RxMagnebind400 RxMagnebind-400 RxRenacidin
Other names
magnesite
02

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)

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