Drug intelligence / Profile preview

magnesium cation

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Intravenous, Intramuscular, Topical
01

Overview

Magnesium cation (Mg2+) is an essential divalent mineral cation that serves as a critical cofactor for over 300 enzymatic systems, including those responsible for protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It is required for energy production, oxidative phosphorylation, and glycolysis, and it contributes to the structural development of bone. In clinical practice, magnesium is administered via various salts (e.g., sulfate, chloride, oxide) for the treatment of hypomagnesemia, cardiac arrhythmias such as Torsades de Pointes, and the prevention of seizures in eclampsia and pre-eclampsia. Research also highlights its role as a bioactive signal in regenerative medicine, particularly in bone tissue engineering where it promotes vascularization and osteogenesis, and its potential neuroprotective effects in conditions like Parkinson's disease.

Brand names
Mag-OxSlow-MagMag-Tab SRMag-Delay
Other names
Mg2+magnesium ionmagnesium(2+)magnesium(II)
02

Targets

NMDAR (Glutamate receptor ionotropic, NMDA)TRPM6TRPM7 (Transient receptor potential cation channel subfamily M member 7)

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