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magnesium chloride + dextrose monohydrate + calcium chloride + sodium lactate + sodium chloride
- Development stage
- Approved
- Lead developer
- Takeda
- Modality
- Small Molecules
- Administration
- Intraperitoneal
01
Overview
**Magnesium chloride + dextrose monohydrate + calcium chloride + sodium lactate + sodium chloride** is a multi-electrolyte, dextrose-based peritoneal dialysis solution. Dextrose establishes an osmotic gradient across the peritoneal membrane to promote ultrafiltration and removal of excess water and solutes, while sodium, lactate, calcium, and magnesium provide electrolyte and buffer support during dialysis. It is administered intraperitoneally for peritoneal dialysis in renal failure. Products containing this exact active-ingredient set include DELFLEX and DIANEAL formulations, which are supplied in multiple dextrose strengths and calcium/magnesium concentrations. ([dailymed.nlm.nih.gov](https://dailymed.nlm.nih.gov/dailymed/drugInfo.cfm?setid=a98facd6-9daa-4d37-8209-63a0599dbfaa))
- Brand names
- DELFLEXDIANEAL PD-2 WITH DEXTROSEDIANEAL LOW CALCIUM WITH DEXTROSE
- Other names
- dextrose peritoneal dialysis solution
02
Targets
AQP1 (Aquaporin-1)
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