Drug intelligence / Profile preview

magnesium chloride + sodium acetate + potassium chloride + sodium chloride + sodium gluconate

Development stage
Unknown
Lead developer
Baxter Healthcare Corporation
Modality
Small Molecules
Administration
Intravenous, Topical
01

Overview

Magnesium chloride + sodium acetate + potassium chloride + sodium chloride + sodium gluconate is a **balanced isotonic crystalloid electrolyte solution** used as an intravenous fluid replacement product and, in closely related presentation-specific products, as a sterile irrigation solution. It is marketed most notably as **Plasma-Lyte A** for injection and **Physiosol/Physiolyte** for irrigation. The combination supplies sodium, potassium, magnesium, chloride, acetate, and gluconate in physiologically balanced concentrations, thereby restoring extracellular fluid volume and electrolyte composition while also providing an **alkalinizing effect** because acetate and gluconate are metabolized to bicarbonate. Clinically it is used as a source of water and electrolytes, for hydration and prevention or treatment of dehydration and electrolyte disturbances, and for general irrigation, washing, and rinsing depending on formulation. It is a **small-molecule electrolyte combination product**, not a biologic, and has been developed/manufactured by companies including Baxter and Abbott, with Hospira-associated irrigation products also cited in public labeling context.

Brand names
Plasma-Lyte APhysiosolPhysiolyte
Other names
multiple electrolytes injection type 1multiple electrolytes injection type 1 pH 7.4multiple electrolytes injection type 1 pH 5.5balanced multi-electrolyte intravenous solutionbalanced electrolyte irrigation solution

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