Drug intelligence / Profile preview

magnesium gluconate

Development stage
Unknown
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Oral, Intravenous
01

Overview

Magnesium gluconate is a mineral supplement used to prevent and treat low levels of magnesium in the blood (hypomagnesemia). Magnesium is an essential mineral involved in over 300 enzymatic reactions in the body, including protein synthesis, muscle and nerve function, blood glucose control, and blood pressure regulation. It plays a critical role in energy production (oxidative phosphorylation and glycolysis), maintenance of normal cellular membrane potential by competing with calcium for binding sites on cell membranes and stimulating calcium sequestration by the sarcoplasmic reticulum. This helps maintain low resting intracellular free calcium ion concentration necessary for various cellular functions. Magnesium gluconate is often preferred as a supplement due to its high bioavailability among magnesium salts[1][3][4][8].

Brand names
Mag-GMagonateMagonate NatalMagtrate
Other names
magnesium gluconate
02

Targets

MG (Mycoplasma gallisepticum)CaV (Voltage-gated calcium channel protein complex)

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