magnesium hexacyanoferrate

Magnesium hexacyanoferrate is an inorganic compound composed of magnesium and the hexacyanoferrate anion. It has recently been developed as a nanocatalyst for biomedical applications, particularly as a cardioprotective agent to attenuate anthracycline (e.g., doxorubicin)-induced cardiotoxicity. The mechanism involves efficient intracellular ferrous ion capture and antioxidation, with prominent superoxide radical dismutation and catalytic hydrogen peroxide decomposition activities. These properties enable it to eliminate cytotoxic radical species in cardiac tissue, providing protection against drug-induced oxidative stress and apoptosis. The compound is typically formulated as a biocompatible nanomedicine using polyvinylpyrrolidone-directed assembly[1][4]. Its clinical development is focused on use during cancer treatment to prevent or reduce chemotherapy-related heart damage.

Other names

magnesium hexacyanoferrate (III)magnesium ferricyanide