Drug intelligence / Profile preview

magnesium sulfate

Development stage
Approved
Lead developer
Giles Chemical
Modality
Small Molecules
Administration
Intravenous, Intramuscular, Oral, Topical
01

Overview

Magnesium sulfate is an inorganic salt used as a medication and supplement. It is primarily indicated for the treatment and prevention of low blood magnesium (hypomagnesemia), control of seizures in pre-eclampsia and eclampsia, management of acute nephritis in children, as a laxative for short-term relief of constipation, and as a soaking solution to relieve minor sprains, bruises, muscle aches or discomfort. Mechanistically, it acts by reducing acetylcholine release at the neuromuscular junction—thereby decreasing striated muscle contractions—and by direct inhibition of action potentials in myometrial muscle cells. It also plays an essential role in many enzyme systems involved with neurochemical transmission and muscular excitability[1][3][5][6].

Brand names
EpsalEpsom SaltRite Aid First Aid Epsom SaltMag 2Mag2Mag-2Magnesium-Rougier
Other names
magnesium sulphate硫酸镁
02

Targets

CaV (Voltage-gated calcium channel protein complex)

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