Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
magnesium sulfate + ropivacaine
- Development stage
- Approved
- Lead developer
- Hospital Universiti Sains Malaysia
- Modality
- Small Molecules
- Administration
- Local Injection
01
Overview
This drug is a combination of magnesium sulfate and ropivacaine, investigated as an analgesic regimen for regional anesthesia. Ropivacaine is a long-acting amide-type local anesthetic that works by blocking voltage-gated sodium channels, thereby inhibiting the conduction of nerve impulses. Magnesium sulfate is added as an adjuvant; it acts as a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist and a calcium channel blocker. The addition of magnesium sulfate is intended to enhance the quality and duration of the sensory block and provide better postoperative pain control while potentially reducing the requirement for systemic opioids. In clinical trials conducted by Hospital Universiti Sains Malaysia, this combination was specifically evaluated for its efficacy in scalp blocks for patients undergoing craniotomy.
- Other names
- magnesium sulfate + ropivacainemagnesium sulphate + ropivacaineMgSO4 + ropivacaine
02
Targets
NMDAR (Glutamate receptor ionotropic, NMDA)CaV (Voltage-gated calcium channel protein complex)NaV (Voltage-gated sodium channels)
Beyond the preview
Go deeper on magnesium sulfate + ropivacaine.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on magnesium sulfate + ropivacaine.