Drug intelligence / Profile preview

mahuang fuzi decoction

Development stage
Unknown
Lead developer
Beijing Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Mahuang Fuzi Decoction is a traditional Chinese medicine (TCM) herbal formula primarily composed of *Ephedra sinica* (Mahuang) and *Aconitum carmichaelii* (Fuzi), often with the addition of *Glycyrrhiza uralensis* (Gancao). It is traditionally used to treat syndromes characterized by Yang deficiency and exterior cold. In modern clinical research, specifically a study led by the Beijing Hospital of TCM (ChiCTR1900021485), it is being evaluated for the treatment of idiopathic membranous nephropathy (IMN) in patients categorized with Shaoyin-Taiyin syndrome according to Liujing syndrome differentiation. The formula is intended to reduce proteinuria and improve renal function by warming the yang, dispersing cold, and promoting diuresis to alleviate edema.

Other names
Mahuang Fuzi Tang麻黄附子汤
02

Targets

NET (Norepinephrine Transporter)NaV (Voltage-gated sodium channels)AR (Adrenergic receptors)

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