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maitake mushroom extract compound
- Development stage
- Unknown
- Lead developer
- Chinese PLA General Hospital
- Administration
- Oral
01
Overview
Maitake mushroom extract compound is a botanical preparation derived from the *Grifola frondosa* fungus, specifically investigated by the Chinese PLA General Hospital as a clinical nutrition intervention for patients with lung and breast cancers. The extract is characterized by its high concentration of bioactive beta-glucans, particularly 1,3-beta-glucan and 1,6-beta-glucan. These compounds function as biological response modifiers that stimulate the innate immune system by binding to pattern recognition receptors like Dectin-1 on macrophages and natural killer (NK) cells. In clinical settings, it is evaluated for its ability to enhance immune function and mitigate the immunosuppressive effects of chemotherapy and radiation therapy.
- Other names
- Grifola frondosa extractmaitake extractmaitake mushroom extract
02
Targets
αMβ2 (Integrin αMβ2)CLEC7A (Dectin-1)
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