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MAN-01 is an investigational small molecule drug candidate developed for the treatment of intraocular eye pressure, specifically targeting Schlemm's Canal in the eye. It is positioned as a first-in-class therapy for conditions such as glaucoma by modulating outflow through this critical anatomical structure[1]. Additionally, under the name "Cannabinoid-MAN01," it has been described as a chemical drug with potential applications in central nervous system diseases. The compound was initially developed by TRx Biosciences Limited and further advanced by Mandara Sciences LLC (Mandara Pharma)[2]. Its mechanism of action and specific molecular targets have not been publicly disclosed.
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