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mandarin oil
- Development stage
- Phase 1
- Lead developer
- UT Health San Antonio
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Inhalation, Topical, Oral
01
Overview
Mandarin oil is an essential oil extracted from the peel of the mandarin orange (*Citrus reticulata*). It is primarily composed of volatile organic compounds, including limonene, gamma-terpinene, and alpha-pinene. In clinical settings, it is utilized as an aromatherapy agent, typically administered via inhalation, to alleviate symptoms such as pain, nausea, and anxiety. The mechanism of action is thought to involve the stimulation of the olfactory system, which subsequently modulates the limbic system and autonomic nervous system to influence emotional and physiological responses. In acute care research, mandarin oil is being investigated for its potential to enhance patient participation in physical and occupational therapy by reducing treatment-limiting symptoms, thereby potentially minimizing hospitalization-related risks and reducing the length of stay.
- Other names
- Citrus reticulata oilMandarin essential oilMandarin orange oil
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