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Manganese ascorbate is a chemical compound comprised of manganese and ascorbic acid (vitamin C) as an organic salt. It is used primarily as a **dietary supplement** to provide both manganese, an essential trace element and enzyme cofactor, and ascorbic acid, a well-known antioxidant. Manganese plays key biochemical roles as a cofactor for numerous enzymes, including Mn superoxide dismutase (MnSOD), arginase, and pyruvate carboxylase, supporting antioxidant defenses, energy metabolism, and connective tissue formation. Ascorbic acid acts as an antioxidant and enhances manganese absorption. Manganese ascorbate is formulated mainly as a **nutrient supplement** and has been included in some combination dietary supplement products for joint health, such as Cosamin DS[1][3][6][10].
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