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Mangoral is an oral diagnostic agent developed by Ascelia Pharma AB, currently in Phase 3 clinical development. It is designed to improve the detection and visualization of focal liver lesions, including liver metastases and primary tumors, in patients with severe renal impairment who are at risk of serious side effects from gadolinium-based contrast agents. Mangoral is a combination drug containing manganese chloride tetrahydrate, L-alanine, and vitamin D3. Its primary mechanism involves manganese acting as an MRI contrast agent to enhance image quality.
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