Drug intelligence / Profile preview

mangosteen juice

Development stage
Preclinical
Lead developer
Xango
Modality
Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

Mangosteen juice is a beverage made from the fruit of *Garcinia mangostana*, commonly known as mangosteen. It is rich in nutrients such as vitamin C, fiber, and unique plant compounds called xanthones, which are believed to have strong antioxidant properties. Mangosteen juice has been studied for its potential health benefits including antioxidant effects (neutralizing free radicals), anti-inflammatory activity (reducing markers like C-reactive protein), immune system support, blood sugar regulation, and possible anticancer effects. Some small clinical studies suggest that regular consumption may increase antioxidant capacity in the bloodstream and reduce inflammation without significant side effects on liver or kidney function[1][3][6]. However, most evidence comes from animal studies or small human trials; large-scale clinical data are lacking. Mangosteen juice is marketed primarily as a dietary supplement or functional food rather than a pharmaceutical drug.

Other names
Garcinia mangostana juicemangosteen fruit juice
02

Targets

AMPK (Adenosine monophosphate–activated protein kinase)SIRT1 (NAD-dependent protein deacetylase sirtuin-1)PGHS-1 (Prostaglandin G/H Synthase 1)CHUK (IKKα)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)

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