Mansoura Univ. EGFR compound 25

Mansoura Univ. EGFR compound 25: sourced facts only. name: "Compounds 21 and 25 were the best EGFR inhibitors having IC50 values of 0.077 and 0.059 µM, respectively, in comparison to Erlotinib (IC50 = 0.04 µM)." [PMID:39912365]; target: "Compounds 21 and 25 were the best EGFR inhibitors having IC50 values of 0.077 and 0.059 µM, respectively, in comparison to Erlotinib (IC50 = 0.04 µM)." [PMID:39912365]; developer: "Pharmaceutical Organic Chemistry Department, Faculty of Pharmacy, Mansoura University, Mansoura, Egypt." [PMID:39912365]; stage: "Finally, compound 25, which was found to be the best dual inhibitor against EGFR and FGFR, was tested for inducing apoptosis and affecting cellular arrest within G2/M phase as well as it was screened to measure its safety towards normal breast cells MCF10a with IC50 value of 47.16 µM in contrast to the reference Staurosporine (IC50 = 18.86 µM)." [PMID:39912365]