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Maqin Kechuan Heji
- Development stage
- Unknown
- Lead developer
- Gansu Provincial Hospital of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Maqin Kechuan Heji is a Traditional Chinese Medicine (TCM) oral liquid formulation developed primarily for the treatment of respiratory conditions such as acute and chronic bronchitis, bronchial asthma, and cough associated with "lung heat" patterns. The preparation is notably associated with the Gansu Provincial Hospital of Traditional Chinese Medicine. Its pharmacological profile is derived from a combination of herbal ingredients, including *Ephedra sinica*, which provides sympathomimetic bronchodilation via beta-adrenergic stimulation, and *Scutellaria baicalensis*, which exerts anti-inflammatory and anti-pyretic effects by inhibiting inflammatory cytokines and enzymes like cyclooxygenase. The mixture is designed to clear heat, resolve phlegm, and alleviate wheezing.
- Brand names
- Maqin Kechuan Heji
- Other names
- 麻芩咳喘合剂Maqin Kechuan Oral Liquid
02
Targets
ADRB2 (β2)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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