Maruho BRD4 compound 12

Maruho BRD4 compound 12: sourced facts only. name: "In this study, we investigate 7-phenoxy-benzimidazole derivative 12, which is a novel BRD4 inhibitor for the treatment of melanoma, by performing scaffold hopping on the previously reported benzimidazole derivative 1." [PMID:39167978]; target: "In this study, we investigate 7-phenoxy-benzimidazole derivative 12, which is a novel BRD4 inhibitor for the treatment of melanoma, by performing scaffold hopping on the previously reported benzimidazole derivative 1." [PMID:39167978]; developer: "Maruho Co., Ltd., Kyoto 600-8815, Japan." [PMID:39167978]; stage: "Notably, compound 12 not only exhibited a favorable pharmacokinetic (PK) profile but also significant tumor growth inhibition in a mouse melanoma xenograft model, indicating its potential as a therapeutic agent for the treatment of melanoma." [PMID:39167978]