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Herb Qu, also known as Shen Qu or Massa Medicata Fermentata, is a traditional Chinese medicine (TCM) preparation produced by the fermentation of a mixture of wheat flour, wheat bran, and various fresh herbs (typically including *Artemisia annua*, *Xanthium sibiricum*, and *Polygonum hydropiper*). In the context of clinical research for amyotrophic lateral sclerosis (ALS), it is being investigated as an adjunctive therapy alongside autologous regulatory T cells (Tregs) and interleukin-2 (IL-2). Traditionally used in TCM to improve digestion and harmonize the stomach, its role in ALS trials likely relates to supporting the "Spleen and Stomach" function, which is a common therapeutic strategy in TCM for neurodegenerative conditions.
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