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Maxing Xiongting Mixture
- Development stage
- Unknown
- Lead developer
- Chongqing City Hospital of Traditional Chinese Medicine
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral
01
Overview
Maxing Xiongting Mixture is a Traditional Chinese Medicine (TCM) hospital preparation developed by the Chongqing Traditional Chinese Medicine Hospital. It is specifically formulated for the treatment of chronic obstructive pulmonary disease (COPD) complicated by hypoxic pulmonary hypertension (HPH). The formula is a modified version of classical TCM prescriptions, likely incorporating *Ephedra sinica* (Ma Huang) and *Prunus armeniaca* (Xing Ren) from the Ma Xing Shi Gan Tang formula, combined with *Ligusticum wallichii* (Chuan Xiong) and *Descurainia sophia* or *Lepidium apetalum* (Ting Li Zi). The mixture is designed to clear lung heat, resolve phlegm, and promote blood circulation to alleviate pulmonary vascular resistance and improve respiratory function. It is currently being evaluated in clinical trials to assess its efficacy in reducing pulmonary artery pressure and improving the quality of life in patients with COPD-associated HPH.
- Other names
- Maxing Xiongting HejiMa Xing Xiong Ting He Ji麻杏芎葶合剂
02
Targets
AR (Adrenergic receptors)
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