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MaxMist Dental
- Development stage
- Preclinical
- Lead developer
- Bennett Pharmaceuticals of America
- Modality
- Small Molecules
- Administration
- Intranasal
01
Overview
MaxMist Dental is a needle-free intranasal anesthetic spray developed by Bennett Pharmaceuticals for dental procedural anesthesia. It is a combination product containing two local anesthetics, tetracaine and bupivacaine, along with the vasoconstrictor phenylephrine. The mechanism of action involves the blockade of voltage-gated sodium channels by tetracaine and bupivacaine, which inhibits nerve conduction and provides regional anesthesia. Phenylephrine acts as a local vasoconstrictor to prolong the duration of the anesthetic effect and minimize systemic absorption. This intranasal delivery system is designed to provide effective anesthesia for dental procedures without the need for traditional needle injections.
- Brand names
- MaxMist Dental
- Other names
- Tetracaine HCl + Bupivacaine HCl + Phenylephrine HCl
02
Targets
SCN5A (Sodium channel protein type 5 subunit alpha)
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