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Drug intelligence / Profile preview
MAXrelief
- Development stage
- Phase 4
- Lead developer
- Akron Pharma
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
MAXrelief is an over-the-counter (OTC) combination analgesic medication marketed by Akron Pharma. It is formulated with a combination of acetaminophen, aspirin, and caffeine, which is a standard regimen for the treatment of migraines and tension headaches. Acetaminophen serves as a non-aspirin pain reliever and antipyretic, while aspirin acts as a nonsteroidal anti-inflammatory drug (NSAID) by irreversibly inhibiting cyclooxygenase enzymes to reduce prostaglandin synthesis. Caffeine is included as an analgesic adjuvant, enhancing the efficacy of the pain relievers through adenosine receptor antagonism and cerebral vasoconstriction. The product is indicated for the temporary relief of minor aches and pains associated with headaches, migraines, the common cold, arthritis, muscular aches, sinusitis, and toothaches.
- Brand names
- MAXrelief
- Other names
- Acetaminophen, Aspirin, and Caffeine
02
Targets
ADORA1 (Adenosine receptor A1 subtype)ADORA2A (Adenosine A₂A Receptor)PGHS-1 (Prostaglandin G/H Synthase 1)PTGS2 (Prostaglandin-Endoperoxide Synthase 2)
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