Drug intelligence / Profile preview

MBRC-201

Development stage
Phase 2
Lead developer
MBrace Therapeutics
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

MBRC-201 is an investigational antibody-drug conjugate (ADC) currently in early-phase clinical trials for advanced, refractory solid tumors, including specific subtypes such as metastatic castration-resistant prostate cancer, non-small cell lung cancer, breast cancer, colorectal cancer, and pancreatic ductal adenocarcinoma. The precise target and payload have not been publicly disclosed. The study aims to assess safety, pharmacokinetics, dose selection, and preliminary antitumor activity in several tumor types. MBRC-201 is being evaluated in multicenter, open-label phase 1/2 trials in heavily pretreated patients with solid tumors[2][3].

Other names
MBRC-201-001MBRC201-001MBRC 201-001

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