Drug intelligence / Profile preview

MCT-475

Development stage
Preclinical
Lead developer
MultiCell Technologies
Modality
Antibody-Based Therapeutics
01

Overview

**MCT-475** is a patent-pending antigen-presenting immunoglobulin therapeutic (IgP) developed by MultiCell Technologies for the treatment of **colorectal cancer** and other solid tumors. It functions by presenting tumor or viral antigens to enhance immune recognition and activation when co-administered with dsRNA therapeutic **MCT-465**, inducing potent anti-tumor and antiviral immunity in preclinical mouse models, including tumor eradication, immune memory, and expansion of cytokine-producing T-cells such as IFNγ and IL-2 producers. No clinical trials have been reported, and development appears to remain at the preclinical stage as of the last available updates around 2012.[1][3][5][7][8]

02

Targets

TLR3 (Toll-like receptor 3)TLR7 (Toll-like receptor 7)TLR8 (Toll-like receptor 8)TNFA (Tumor necrosis factor alpha (soluble))

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