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MD-TISSUE
- Development stage
- Unknown
- Lead developer
- Guna
- Modality
- Recombinant Proteins and Enzymes, Device-based Delivery → Drug Delivery Systems
- Administration
- Intradermal, Percutaneous
01
Overview
MD-TISSUE is a collagen-based medical device developed by Guna S.p.a. specifically for the treatment of tendon-related conditions, including tendinopathies and tendon injuries. The product is composed of porcine-derived Type I collagen, which is supplemented with ancillary substances including ascorbic acid (Vitamin C), magnesium gluconate, pyridoxine hydrochloride (Vitamin B6), riboflavin (Vitamin B2), and thiamine hydrochloride (Vitamin B1). MD-TISSUE functions as a mechanical scaffold that stabilizes and reinforces the extracellular matrix (ECM) of the tendon tissue. By providing this structural support, it influences the morpho-functional properties of tenocytes, thereby promoting the physiological repair process and improving joint mobility while reducing pain. It is typically administered via local injection (periarticular or intra-articular) to the affected area.
- Brand names
- MD-TISSUE
- Other names
- Guna MD-TISSUECollagen Medical Device MD-TISSUE
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