Drug intelligence / Profile preview

MD920

Development stage
Discontinued
Lead developer
AusBio
Modality
Small Molecules
Administration
Topical
01

Overview

MD920 is a topical small molecule investigational drug developed by Aus Bio for the treatment of chronic wounds, specifically hard-to-heal chronic venous leg ulcers. The active ingredient of MD920 is a 1:1 ratio of gibberellic acid and its salt (gibberellic acid and salt 1:1). Gibberellic acid is a naturally occurring plant growth regulator (phytohormone) that has been shown to stimulate cell migration, particularly of fibroblasts, and exhibit anti-inflammatory properties. MD920 was formulated as a topical agent applied to a non-adhesive wound dressing and evaluated in a Phase 2/3 clinical trial in Australia in combination with standard multilayer compression bandaging. However, the trial was stopped early, and the clinical development of MD920 has been discontinued.

Other names
gibberellic acid and salt 1:1

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