Drug intelligence / Profile preview

MDcalm

Development stage
Unknown
Lead developer
MDbio Wellness
Modality
Small Molecules
Administration
Oral
01

Overview

MDcalm is a plant-based dietary supplement developed by MDbio Wellness, specifically formulated to address stress and promote relaxation. Its composition features a synergistic blend of hemp-derived phytocannabinoids, including cannabidiol (CBD) and cannabigerol (CBG), alongside botanical adaptogens and amino acids such as Ashwagandha, L-Theanine, and GABA. The product was evaluated in a large-scale, blinded, placebo-controlled virtual clinical trial conducted by Radicle Science to provide scientific validation of its efficacy in reducing stress and anxiety in real-world populations. MDcalm is designed to modulate the body's stress response by interacting with the endocannabinoid system and the hypothalamic-pituitary-adrenal (HPA) axis.

Brand names
MDcalm
02

Targets

CNR1 (Cannabinoid receptor 1)GABA-B (Gamma-aminobutyric acid receptor type B)GR (Glucocorticoid receptor)

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