Drug intelligence / Profile preview

MDH-032

Development stage: Unknown
Lead developer: MD Healthcare
Modality: Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Lipid-based Nanoparticles → Nanoparticles → Drug Delivery Systems, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics

Overview

MDH-032 is a microbial extracellular vesicle (EV)-based therapeutic candidate under development by MD Healthcare. It is designed to target inflammatory and fibrotic pathways for the treatment of non-alcoholic steatohepatitis (NASH), idiopathic pulmonary fibrosis (IPF), and chronic kidney disease (CKD). MDH-032 utilizes MD Healthcare's proprietary microbial EV platform, which leverages the immunomodulatory and tissue-regenerative properties of commensal bacteria-derived extracellular vesicles to modulate host immune responses and promote tissue repair.

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