Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
MDPK67b
- Development stage
- Phase 1
- Lead developer
- Med Discovery
- Modality
- Therapeutic Enzymes → Recombinant Proteins and Enzymes
- Administration
- Intravenous, Subcutaneous, Topical
01
Overview
MDPK67b is a recombinant protease inhibitor developed by Med Discovery SA for the treatment of prostate cancer. It is designed to target and inhibit human kallikrein-related peptidases (KLKs), specifically KLK2, KLK4, and KLK14. These serine proteases are downstream targets of the androgen receptor (AR) and play significant roles in prostate cancer progression and the transition to castration-resistant states. By inhibiting these secreted KLKs, MDPK67b aims to downregulate AR signaling, reduce cell proliferation, and induce apoptosis in tumor cells. The drug has been evaluated in Phase I clinical trials for safety and pharmacokinetics in healthy volunteers and in Phase Ib studies for preoperative treatment in patients with untreated prostate cancer.
- Other names
- KLK inhibitor MDPK67b
Beyond the preview
Go deeper on MDPK67b.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on MDPK67b.