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ME001 is a peptide-based therapeutic being developed by Letolab for the treatment of obesity and non-alcoholic steatohepatitis (NASH). It functions as an agonist of the glucagon-like peptide-1 (GLP-1) receptor and targets an additional, undisclosed biological pathway. This dual-targeting approach is intended to provide synergistic metabolic benefits, addressing both weight reduction and the underlying liver pathology associated with NASH. The drug is currently in the IND-enabling stage of development.
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