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Measles, Mumps, and Rubella Virus Vaccine Live is a trivalent live-attenuated vaccine designed to provide active immunity against measles (rubeola), mumps, and rubella (German measles). This specific drug entry refers to the vaccine as utilized in clinical development programs by Sanofi Pasteur, particularly in studies evaluating the safety and immunogenicity of concomitant administration with other pediatric vaccines, such as the quadrivalent meningococcal conjugate vaccine (MenACYW/MenQuadfi). The vaccine contains weakened strains of the measles, mumps, and rubella viruses that replicate at a low level to stimulate a robust immune response, including the production of neutralizing antibodies and memory T cells, without causing the diseases in healthy individuals. In the context of Sanofi's meningococcal trials, the MMR vaccine is administered to infants and toddlers to ensure that co-vaccination does not interfere with the protective immune response of either the routine or the investigational vaccine.
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