Drug intelligence / Profile preview

measles, mumps, rubella and varicella virus vaccine live + pneumococcal 7-valent conjugate vaccine

Development stage
Unknown
Lead developer
Merck
Modality
Vaccines & Immunotherapeutics
Administration
Subcutaneous, Intramuscular
01

Overview

This combination refers to the concurrent administration of the live-attenuated measles, mumps, rubella, and varicella (MMRV) vaccine and the 7-valent pneumococcal conjugate vaccine (PCV7). The MMRV component (such as ProQuad or Priorix-Tetra) provides immunity against four viral pathogens, while the PCV7 component (Prevnar) protects against invasive diseases caused by seven serotypes of Streptococcus pneumoniae. This regimen is a standard part of pediatric immunization schedules, typically administered to children between 12 and 15 months of age. The combination has been extensively studied to ensure that co-administration does not compromise the immunogenicity or safety profile of either vaccine.

Brand names
ProQuadPrevnarPriorix-Tetra
Other names
MMRV + PCV7ProQuad + Prevnar
02

Targets

MV (Measles virus)Mumps virus antigenCPS14 (Streptococcus pneumoniae capsular polysaccharide serotype 14)CPS 18C (Streptococcus pneumoniae capsular polysaccharide serotype 18C)CPS19F (Streptococcus pneumoniae capsular polysaccharide serotype 19F)CPS23F (Streptococcus pneumoniae capsular polysaccharide serotype 23F)CPS4 (Streptococcus pneumoniae capsular polysaccharide serotype 4)6B CPS (Streptococcus pneumoniae serotype 6B capsular polysaccharide)Streptococcus pneumoniae capsular polysaccharide serotype 9V (PnPS 9V)VZV (Varicella-zoster virus)Streptococcus pneumoniae serotype 19F capsular polysaccharide9V CPS (Streptococcus pneumoniae serotype 9V capsular polysaccharide)

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