Drug intelligence / Profile preview

measles and rubella vaccine

Development stage
Phase 2
Lead developer
Micron Biomedical
Modality
Vaccines & Immunotherapeutics
Administration
Transdermal, Subcutaneous
01

Overview

The measles rubella vaccine (MRV) is a bivalent combination vaccine containing live-attenuated strains of the measles and rubella viruses. It is designed to elicit a protective immune response, characterized by the production of specific IgG antibodies and neutralizing titers against both pathogens. While traditionally administered via subcutaneous injection, recent development efforts by Micron Biomedical have focused on a microneedle patch (MRV-MNP) delivery system. This technology aims to provide a stable, easy-to-administer, and less invasive alternative to needle-and-syringe vaccinations, particularly for use in infants and toddlers in low-resource settings. The MRV-MNP is currently being evaluated in Phase 1/2 clinical trials to assess its safety and immunogenicity compared to standard subcutaneous administration.

Other names
MRVMR vaccineMeasles-Rubella Vaccine
02

Targets

B-cell receptors specific for measles H/F and rubella E1/E2 antigensCD46 (CD46 Molecule)PVRL4 (Nectin cell adhesion molecule 4)RNA-sensing pattern recognition receptor

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