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The measles-mumps-rubella-varicella (MMRV) vaccine is a combination live attenuated viral vaccine that provides immunization against four diseases: measles, mumps, rubella (German measles), and varicella (chickenpox). It is administered as a single injection to children typically between 12 months and 12 years of age. The mechanism of action involves stimulating the immune system to produce antibodies against each virus without causing disease. This confers long-lasting immunity in most recipients. The primary indication for the MMRV vaccine is the prevention of these four infectious diseases in pediatric populations. Major brands include ProQuad (Merck) and Priorix Tetra (GSK)[8][1][3].
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