Drug intelligence / Profile preview

Mechnikov probiotics

Development stage
Unknown
Modality
Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
Administration
Oral
01

Overview

**Mechnikov probiotics** is an orally administered probiotic product evaluated as a perioperative adjunct in patients undergoing anterior resection for sigmoid colon cancer. In the registered double-blind, randomized, placebo-controlled study NCT03531606, participants received one packet twice daily for four weeks, beginning one week before surgery and continuing for three weeks after surgery; the stated objectives included assessment of postoperative anterior resection syndrome symptoms, bowel function, quality of life, inflammatory markers, nutritional status, complications, gut microbiota, and short-chain fatty acids. The public trial record does not identify the constituent microbial strains, viable counts, manufacturer, or a defined molecular target; therefore it cannot be resolved to a specific INN or strain-level live biotherapeutic product. ([clinicaltrials.gov](https://clinicaltrials.gov/study/NCT03531606))

Brand names
Mechnikov probiotics
Other names
Mechnicov probioticsMetchnik probiotic

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