meclizine

Meclizine is a piperazine-derivative antihistamine classified as an anticholinergic antiemetic. It is primarily used to prevent and treat nausea, vomiting, and dizziness associated with motion sickness and to manage vertigo caused by diseases affecting the vestibular system. Meclizine acts as a histamine H1 receptor antagonist with additional anticholinergic and central nervous system depressant properties. Its mechanism of action involves depressing labyrinth excitability and conduction in vestibular-cerebellar pathways[5][7]. The drug is available in oral tablet forms (including chewable) for adults and children aged 12 years or older[3]. Developed by Pfizer.

Brand names

AntivertBonineBonine MaxDramamine Less DrowsyDramamine Nausea Long LastingAntrizineTravel-Ease

Other names

meclizine hydrochloride