Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
mecobalamin + pregabalin
- Development stage
- Unknown
- Lead developer
- Zinnia Life Sciences
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Pregadyne M is a fixed-dose combination capsule containing pregabalin and mecobalamin (methylcobalamin), developed by Zinnia Life Sciences. It is indicated for the treatment of neuropathic pain, such as diabetic neuropathy, postherpetic neuralgia, and spinal cord injury-related nerve pain. Pregabalin acts as an alpha-2-delta ligand that modulates voltage-gated calcium channels to reduce the release of excitatory neurotransmitters, thereby decreasing pain signaling. Mecobalamin, an active form of vitamin B12, promotes myelin sheath synthesis and supports the regeneration and repair of damaged nerve fibers.
- Brand names
- Pregadyne M
- Other names
- Pregadyne M 75Pregadyne M 750mcg/75mgmethylcobalamin + pregabalinpregabalin + mecobalaminpregabalin + methylcobalamin
02
Targets
CACNA2D1 (Voltage-gated calcium channel subunit alpha2/delta-1)CACNA2D2 (Voltage-gated calcium channel subunit alpha-2/delta-2)MTR (Methionine synthase)α2δ (Voltage-gated calcium channel alpha-2-delta subunit)
Beyond the preview
Go deeper on mecobalamin + pregabalin.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on mecobalamin + pregabalin.