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Drug intelligence / Profile preview
medical cannabis oil
- Development stage
- Phase 3
- Lead developer
- M.H. MediCane
- Modality
- Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
- Administration
- Oral, Sublingual
01
Overview
Medical cannabis oil (specifically MediCane's balanced T3:C3 oil) is an oral, sublingually administered botanical extract formulated in GMP-grade olive oil. It contains a balanced 1:1 ratio of tetrahydrocannabinol (THC) and cannabidiol (CBD) derived from a proprietary cannabis strain. Developed by M.H MediCane in collaboration with Dr. Reddy's Laboratories, the formulation was investigated as an add-on therapy to standard of care for the treatment of agitation and behavioral disturbances (Behavioral and Psychological Symptoms of Dementia, or BPSD) in adults with major neurocognitive disorder (dementia), including probable Alzheimer's disease. The clinical development for this indication was evaluated in a Phase II trial in Israel (NCT06217146), which was subsequently terminated.
- Brand names
- Medicane Oil T3C3 BalancedT3C3 Balanced OilT-3C3 Balanced OilT 3C3 Balanced Oil
- Other names
- balanced T3:C3 medical cannabis oilmedical cannabis oilMediCane T3:C3 medical cannabis oil
02
Targets
HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))CNR1 (Cannabinoid receptor 1)GPR55 (G protein-coupled receptor 55)TRPV1 (Transient receptor potential cation channel subfamily V member 1)
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