Drug intelligence / Profile preview

medical collagen sponge

Development stage
Unknown
Lead developer
Innocoll, Inc.
Administration
Topical, Implant
01

Overview

Medical collagen sponges are absorbable biomaterials composed primarily of purified Type I or microfibrillar collagen. They are widely used in surgical and wound care settings to promote hemostasis (control bleeding), support tissue regeneration, and as carriers for local drug delivery such as antibiotics or anti-inflammatory agents. These sponges enhance platelet aggregation and fibrin formation at the site of application, facilitating clot formation and wound healing[3][4][2]. In clinical practice, they are applied topically to wounds or surgical sites and can be loaded with drugs like gentamicin for infection control in chronic osteomyelitis[1]. The porous structure allows for cell attachment, proliferation, nutrient flow, and controlled release of incorporated medications[4][2].

Brand names
Avitene Ultrafoam Collagen SpongeSpongeCol
Other names
absorbable collagen spongeantibiotic-loaded collagen spongemicrofibrillar collagen hemostat
02

Targets

GPVI (Platelet glycoprotein VI)GP9 (Platelet glycoprotein ib-ix-v complex)ITGA2/ITGB1 (Integrin alpha-2/beta-1 receptor)

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