Drug intelligence / Profile preview

medical marijuana

Development stage
Unknown
Lead developer
Colorado State University
Modality
Small Molecules
Administration
Inhalation
01

Overview

Medical marijuana, in the context of research conducted by Colorado State University, refers to the use of specific strains of the *Cannabis sativa* plant characterized by varying ratios of delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD). This specific investigational program evaluates the impact of three distinct potency profiles—high CBD/low THC, high THC/low CBD, and balanced THC/CBD—on motor and cognitive functions in patients with multiple sclerosis (MS). THC acts primarily as a partial agonist at the CB1 and CB2 cannabinoid receptors, which are involved in modulating pain, muscle spasticity, and inflammation. CBD is a non-psychoactive cannabinoid that modulates the endocannabinoid system and various non-cannabinoid receptors, potentially providing neuroprotective and anti-inflammatory benefits while mitigating the psychoactive side effects of THC. The goal of the Colorado State University study is to provide evidence-based data on the safety and efficacy of different cannabinoid ratios for managing MS symptoms.

Other names
cannabismarijuanaTHC + CBDmedical cannabis
02

Targets

CNR1 (Cannabinoid receptor 1)

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